Currently Enrolling Studies

​Chronic Low Back Pain -  Flier
         Moderate-to-Severe chronic low back pain(CLBP) requiring opioid analgesia for an extended period of time.
Type 2 Diabetes -
          
The primary efficacy objective of this trial is to evaluate the placebo-adjusted change in hemoglobin

A1c (HbA1c) from baseline after 24 weeks of exposure to Study Medication in type 2 diabetic subjects at

high risk of cardiovascular adverse events.


Chronic Low Back Pain -
          The primary objective of the study is to evaluate the efficacy of Study Medication compared to placebo in reducing low back pain (LBP), as measured by the change from baseline at week 16 in the average daily LBP intensity (LBPI) numerical rating scale (NRS) score.

Osteoarthritis of the Hip or Knee -

         This is a randomized, double-blind, placebo-controlled, multicenter, parallel-group, Phase 3 study of the efficacy and safety of Study Medication  for 16 weeks compared to placebo in subjects with osteoarthritis of the knee or hip.
Osteoarthritis of the Knee -

​         The study is a multi-center, multinational, randomized, double-blind, placebo-controlled, parallel-group 

phase III clinical trial in subjects with OA of the knee. Subjects with diagnosed OA in at least one knee will be

randomized to treatment with either Study Medication or placebo.       


Fibromyalgia -

         This is a randomized, double-blind, double-dummy, placebo- and active controlled, multi-center

study of Study Medication  in subjects with pain associated with fibromyalgia.





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